Hypercalcaemia during resolution of calcinosis in juvenile dermatomyositis.

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چکیده

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Treatment of calcinosis with biphosphonates in juvenile dermatomyositis

Juvenile dermatomyositis (JDM) is a multisystem disease that is characterized by nonsuppurative inflammation of striated muscle and skin. Dystrophic calcification occurs in up to 40% of children We present our treatment approach in four JDM patients with calcinosis. Four female patients (median age 8.5 years, range 6–14) had been diagnosed as JDM in our center. Two of them presented with severe...

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Ureteral calcinosis in juvenile dermatomyositis: successful precocious surgical management.

We report a successful surgical intervention to repair bilateral ureteral strictures in a child with juvenile dermatomyositis (JDM) and ureteral calcinosis. This is the fourth reported case in medical literature. A 9-year-old-girl with severe JDM, a rare connective tissue disease characterized by skin and muscles vasculitis, was under immunosuppressive therapy. In the course of the disease, she...

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Severe calcinosis cutis with cutaneous ulceration in juvenile dermatomyositis.

BACKGROUND Calcinosis cutis is usually seen in long standing and untreated cases of juvenile dermatomyositis. CASE CHARACTERISTICS 7-year-old girl with severe calcinosis cutis who developed cutaneous ulceration, rash and myopathy. OBSERVATION Myopathic changes in EMG, muscle edema in MRI, elevated muscle enzymes and Jo-1 positive antibodies. OUTCOME Treatment with prednisolone and methotr...

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Calcinosis as a complication of juvenile dermatomyositis (JDM)

Results 17/42 developed calcinosis associated with earlier onset of the disease, male predominance and chronic. Calcium deposits were classified as: superficial nodular, deep nodular, mass, linear or mixed deposits and calcinosis universalis. 80% had two or more types of deposits. The anatomical areas more frequently affected were the thighs and forearms. Complications included: drainage, chron...

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Risk factors associated with calcinosis of juvenile dermatomyositis.

OBJECTIVE To identify risk factors associated with calcinosis in children and adolescents with juvenile dermatomyositis. METHODS A review was carried out of the medical records of 54 patients with juvenile dermatomyositis. Data were collected on demographic characteristics, clinical features: muscle strength (stages I to V of the Medical Research Council scale), pulmonary involvement (restric...

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ژورنال

عنوان ژورنال: BMJ

سال: 1984

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.288.6427.1345